Products & Technology

 
  • The BioTwin Chips offer a flexible 3D cell culture platform to facilitate various experimental designs, enabling you to turn your conceptual ideas into feasible experiments.
  • Each BioTwin Chip consists of four units, allowing you to run different experimental designs simultaneously.
 
  • The BioTwin Chips allow for live monitoring of experiments using an optical microscope before advancing to confocal microscopy.
  • The platform supports full-thickness tri-layer tissue modelling, including epithelial, stromal, and endothelial interfaces, and is compatible with immune cell trafficking assays, barrier integrity assessment, cytokine profiling, and antibody penetration studies.

 

  • Each unit features three channels: Channel A, the Extracellular Matrix (ECM) channel, and Channel B. The ECM channel accommodates any single type or combination of ECM types relevant to your experiment. Channels A and B are designed for your cells or mixed cell types of interest.
  • The BioTwin Chip is engineered to reduce exposure-driven variability by ensuring the uniform distribution of flow and compound delivery across multiple parallel tissue units.
 
  • BioTwin Chips are an advanced ECM-based system that allows you to grow size-controlled microtissues in situ. This eliminates the need for plate transfers, simplifying your workflow while enabling the comprehensive evaluation of cell-cell and cell-matrix interactions for various downstream applications.
  • The platform integrates mirrored tissue units arranged around a shared ECM core, enabling matched exposure conditions across parallel replicates within a single device.

Our Process and Capabilities

Easy to use

  • One-step operation
  • High cell survival rate
  • Easy observation
  • Optical transparent
  • Formation of microtissues in situ

Microscope compatible

  • Optical microscope
  • Confocal microscope
  • High content screening system

Suitable for various applications

  • Cell-cell and cell-matrix interaction
  • Cancer and Immuno-oncology research
  • Therapeutics research
  • Toxicology and Developmental biology
  • Other research applications

Featured Applications